Full Testosterone Replacement · TRT

The DRIVE Protocol

Testosterone Cypionate · Injection Testosterone · Cream

Clinical-grade testosterone cypionate
Lab work and follow-ups included
Cold-chain shipped from licensed pharmacy

Weekly injection, subQ or IM · Cold-chain shipment

Choose your starting dose

100 MG

Starter dose

150 MG

Standard

200 MG

High-end

$149 / month

$447 billed every 12 weeks

Prescription only Free shipping Provider review in 24h US-licensed pharmacy

Important safety information

Daily topical — no needles
Same clinical oversight as injections
Room-temperature shipment

Daily, applied to skin · Room-temperature shipment

Choose your starting dose

50 MG/pump

Starter dose

100 MG/pump

Standard

150 MG/pump

High-end

$149 / month

$447 billed every 12 weeks

Prescription only Free shipping Provider review in 24h US-licensed pharmacy

Important safety information

What It Is

Full testosterone replacement — with the monitoring to match.

Brings testosterone back to where it should be
Choose injection or cream — labs included
More energy, better mood, stronger body
Convenient — shipped directly to your door

Compare Your Options

Injection

Testosterone Cypionate

Best for

Stronger peaks and once-weekly simplicity

What's good

Direct delivery — rapid absorption
Higher peak testosterone levels
Only once per week
Gold standard for TRT

Price$149/mo

Onset2-4 weeks

FreqWeekly

FormatIM/SubQ

$127/mo (save $22)

Cream

Testosterone Topical

Best for

Smoother daily levels without injections

What's good

Steady absorption throughout the day
No needles — applied to skin
More stable hormone levels
Simple daily morning routine

Price$149/mo

Onset3-6 weeks

FreqDaily

FormatTopical

$127/mo (save $22)

Featured Image images/drive-science.png

How it works

How Drive actually works.

Drive is bio-identical testosterone — the same molecule your body already makes — delivered as a weekly injection or topical cream that keeps your levels steady in the optimal range.

Most men feel the difference within four weeks: steadier energy, sharper focus, better recovery. Your provider tracks labs and titrates the dose so you stay in range without overshooting.

Drive Protocol · Testosterone cypionate

Board-certified physicianslicensed in your state

Compounded by a US pharmacylicensed, audited, traceable

Free, discreet shippingincluded in your subscription

What You’ll Take

A regimen, not a single pill.

Your provider prescribes each component separately. Each item ships from a licensed pharmacy.

Why This Protocol

Clinical-grade TRT, at home.

The same testosterone protocol used in men's health clinics — lab work, dosing, and follow-ups included.

About this protocol

Technical and clinical context our providers use when evaluating intake for hormone-optimization therapy.

What is testosterone cypionate?

Full hormone replacement — long-acting esterified testosterone, the clinical gold standard
Supports the symptoms low T affects most — energy, libido, mood, muscle, bone density
Weekly self-injection or daily transdermal cream — your provider picks the route
Two morning labs confirm low T before prescribing. Follow-up review at 8–12 weeks.
For men with confirmed low T who want full replacement, not a workaround

The DRIVE Protocol — Testosterone Cypionate

Storage & handling

Store at controlled room temperature (68–77°F / 20–25°C).
Keep upright and away from direct sunlight.
Inspect each dose — discard if cloudy, discolored, or contains particulates.
Each shipment includes alcohol pads, syringes, and a sharps container.
Compounded under USP <797> sterile guidelines in a licensed US pharmacy.
Schedule III controlled substance — store securely and out of reach of others.

Your TRT Arc

Week 1-2

First doses administered. Your body begins adjusting to new testosterone levels.

Month 1

Energy, mood, and motivation start shifting. Lab work confirms levels are rising.

Month 3

Full effects emerging — body composition, strength, and mental clarity.

Month 6+

Optimized and stable. Provider fine-tunes your protocol based on labs.

Your timeline to treatment

From personalized intake to ongoing support, we help you get — and stay — on track.

Start The DRIVE Protocol in 5 simple steps

Answer a few questions about your health, goals, and history — all online, no in-person appointment needed. You'll find out if you're eligible within 24 hours.

A US-licensed clinician reviews your intake, follows up on anything that needs clarification, and signs your prescription — typically within 24 hours.

A licensed clinician reviews your intake

Your Rx is compounded in a US-licensed 503A pharmacy under USP <797> sterile standards, lab-tested, sealed, and shipped — never sitting on a shelf.

US-licensed 503A pharmacy compounds your Rx

Your shipment lands at your door — refrigerated where required, with everything you need to start: vials, alcohol pads, syringes, and step-by-step guidance.

Ongoing care from our medical team — quick re-checks, dose adjustments when needed, and 24/7 access to your provider whenever a question comes up.

Sources & References

▾

Peer-reviewed research and regulatory documents our medical team consults when evaluating intake for this protocol.

FDA / DailyMed

Depo-Testosterone (testosterone cypionate injection, USP CIII) Prescribing Information

FDA-approved label for branded testosterone cypionate (NDA 085635) — DailyMed auto-updates to the current FDA-approved label., defining indications for primary and hypogonadotropic hypogonadism, dosing, warnings, and Schedule III status.
2018

View source

American Urological Association

Evaluation and Management of Testosterone Deficiency: AUA Guideline

AUA's multidisciplinary clinical guideline on diagnosing and treating testosterone deficiency, including thresholds, work-up, and monitoring of men on testosterone therapy.
Mulhall JP et al. — Journal of Urology 2018

View source

Endocrine Society

Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline

Evidence-based recommendations for diagnosing hypogonadism only in symptomatic men with consistently low serum testosterone and for initiating and monitoring testosterone therapy.
Bhasin S et al. — Journal of Clinical Endocrinology & Metabolism 2018

View source

New England Journal of Medicine

Cardiovascular Safety of Testosterone-Replacement Therapy

TRAVERSE trial (n=5,246) found testosterone replacement was noninferior to placebo for major adverse cardiac events in hypogonadal men at high cardiovascular risk, though atrial fibrillation, acute kidney injury, and pulmonary embolism occurred more often on testosterone.
Lincoff AM et al. — New England Journal of Medicine 2023

View source

New England Journal of Medicine

Effects of Testosterone Treatment in Older Men

Pivotal T-Trials report: testosterone gel for one year in men 65+ with low testosterone produced moderate benefits in sexual function and modest benefits in physical function and mood versus placebo.
Snyder PJ et al. — New England Journal of Medicine 2016

View source

JAMA

Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment

T-Trials cognitive sub-study: one year of testosterone therapy did not improve memory or other cognitive functions versus placebo in older men with age-associated memory impairment.
Resnick SM et al. — JAMA 2017

View source

United States Pharmacopeia

USP General Chapter <797> Pharmaceutical Compounding - Sterile Preparations

Official USP standard (effective November 1, 2023) governing personnel, facilities, environmental monitoring, beyond-use dating, and quality controls for compounded sterile preparations such as injectable testosterone cypionate.
2023

View source

U.S. Drug Enforcement Administration

Drug Scheduling

DEA reference confirming anabolic steroids, including testosterone, are Schedule III controlled substances under the Controlled Substances Act (21 USC 802 et seq.).
2024

View source

U.S. Food and Drug Administration

Human Drug Compounding

FDA hub explaining the regulatory framework for compounded drugs under the Drug Quality and Security Act, including Section 503A pharmacies and Section 503B outsourcing facilities.
2024

View source

ClinicalTrials.gov (U.S. National Library of Medicine)

The Testosterone Trials in Older Men (NCT00799617)

NIH-funded registry record for the coordinated set of seven Testosterone Trials (sexual, physical, vitality, cognitive, bone, cardiovascular, anemia) in 790 men aged 65+ with low testosterone.
2018

View source

Medical notice. The DRIVE Protocol is a Schedule III controlled prescription medication dispensed only after a licensed clinician's review of your intake and lab-confirmed hypogonadism on two morning serum draws. Not appropriate for personal or family history of prostate or breast cancer, severe untreated sleep apnea, uncontrolled heart failure, or polycythemia. Cardiovascular safety in older men was studied in TRAVERSE (NEJM 2023) — discuss with your physician. Statements on this site have not been evaluated by the FDA.

Pairs With

What Drive stacks with.

The protocols our providers most often add alongside this one.

Enclomiphene · Hormone Optimization

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The DRIVE Protocol

Full testosterone replacement — with the monitoring to match.

Injection

Cream

How Drive actually works.

A regimen, not a single pill.

Clinical-grade TRT, at home.

About this protocol

Your timeline to treatment

Sources & References

Depo-Testosterone (testosterone cypionate injection, USP CIII) Prescribing Information

Evaluation and Management of Testosterone Deficiency: AUA Guideline

Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline

Cardiovascular Safety of Testosterone-Replacement Therapy

Effects of Testosterone Treatment in Older Men

Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment

USP General Chapter <797> Pharmaceutical Compounding - Sterile Preparations

Drug Scheduling

Human Drug Compounding

The Testosterone Trials in Older Men (NCT00799617)

What Drive stacks with.

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